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Symbol
Name
ID

Dkc1
dyskeratosis congenita 1, dyskerin
MGI:1861727

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Leukopenia	Abnormality of neutrophils	Acute myeloid leukemia	Periodontitis	Conjunctivitis	Blepharitis	Splenomegaly	Immunodeficiency	Cellular immunodeficiency	Recurrent respiratory infections
Disease(s) Associated with DKC1	Leukopenia	Abnormality of neutrophils	Acute myeloid leukemia	Periodontitis	Conjunctivitis	Blepharitis	Splenomegaly	Immunodeficiency	Cellular immunodeficiency	Recurrent respiratory infections
dyskeratosis congenita
X-linked dyskeratosis congenita

Mouse Phenotypes

enlarged spleen

decreased B cell number

decreased pre-B cell number

decreased T cell number

decreased lymphocyte cell number

decreased leukocyte cell number

abnormal spleen morphology

decreased spleen red pulp amount

decreased spleen white pulp amount

abnormal immune system cell morphology

abnormal immune system organ morphology

lung inflammation

Availability

Mouse Genotype

Dkc1^tm1Ppp/Dkc1⁺

Dkc1^tm1.1Pjma/Y

Dkc1^tm1Ppp/Y

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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